AbstractThe serostatus of five abortigenic agents and the association between abortion history and Coxiella burnetii seropositivity were assessed in 350 dairy cattle from Al Ain, UAE. The bovine sera were ELISA-screened for C. burnetii, Leptospira Hardjo, Neospora caninum, and Brucella abortus antibodies, plus bovine pestivirus (BVDV) antigen. The serology data were collated and the level of significance between the proportions of C. burnetii-seropositive cattle with and without abortion history assessed by the Z test of two proportions. Of the 350 cattle, 41.4%, 1.7%, 1.4%, 0.3%, and 0.0% were seropositive to the above pathogens, respectively. Besides, 61.9%, 2.9%, 1.0%, 0.0%, and 0.0% of the 105 cattle with history of abortion and 32.7%, 1.2%, 1.6%, 0.0% and 0.0% of the 245 seropositive cattle with no history of abortion were also seropositive for the above pathogens respectively. Moreover, the proportion of C. burnetii-seropositive cattle with history of abortion were significantly higher than the C. burnetii-seropositive ones without abortion history (p-value < 0.01). Apparent C. burnetii infections were relatively higher than the other four pathogens suggesting this bacterium contributed to abortion in the herd. Additional research on the public and bovine health implications of C. burnetii and Leptospira in the UAE are urgently needed.
Abu Dhabi Food Control Authority. 2011. Farm Animal Diseases Epidemiology and Control Guidelines, Code of Practice, No 7, June 2011.
Afzal M. & Sakkir M. 1994. Survey of antibodies against various infectious disease agents in racing camels in Abu Dhabi, United Arab Emirates. Rev Sci Tech, 13, 787-792.
Agerholm J.S. 2013. Coxiella burnetii associated reproductive disorders in domestic animals - A critical review. Acta Vet Scand, 55, 13.
Ali H., Ali A.A., Atta M.S. & Cepica A. 2012. Common, emerging, vector-borne and infrequent abortigenic virus infections of cattle. Transbound Emerg Dis, 59, 11-25.
Aslan M.E., Azkur A.K. & Gazyagci S. 2015. Epidemiology and genetic characterization of BVDV, BHV-1, BHV-4, BHV-5 and Brucella spp. infections in cattle in Turkey. J Vet Med Sci, 77, 1371-1377.
Asmare K., Sibhat B., Ayelet G., Gebremedhin E.Z., Lidete K.A & Skjerve E. 2018. Serological evidence of bovine herpesvirus-1, bovine viral diarrhea virus and Schmallenberg virus infections in relation to reproductive disorders in dairy cattle in Ethiopia. Acta Trop, 178, 236-241.
Azizzadeh M., Mohammadi G., Haghparast A. & Heidarpour-Bami M. 2012. Seroepidemiology of Coxiella burnetii in commercial dairy herds in northeast of Iran. Iran J Vet Sci Technol, 3, 33-40.
Bildfell R.J., Thomson G.W., Haines D.M., McEwen B.J. & Smart N. 2000. Coxiella burnetii infection is associated with placentitis in cases of bovine abortion. J Vet Diagn Invest, 12, 419-425.
Cabassi C.S., Taddei S., Donofrio G., Ghidini F., Piancastelli C., Flammini C.F. & Cavirani S. 2006. Association between Coxiella burnetii seropositivity and abortion in dairy cattle of Northern Italy. New Microbiol, 29, 211-214.
Chaber A.L., Lloyd C., O'Donovan D., McKeown S., Wernery U. & Bailey T. 2012. A serologic survey for Coxiella burnetii in semi-wild ungulates in the Emirate of Dubai, United Arab Emirates. J Wildl Dis, 48, 220-222.
Chastant-Maillard S. 2015. Impact of bovine herpesvirus 4 (BoHV-4) on reproduction. Transbound Emerg Dis, 62, 245-251.
Delooz L., Czaplick G., Gregoire F., Dal Pozzo F., Pez .F, Kodjo A. & Saegerman C. 2018. Serogroups and genotypes of Leptospira spp. strains from bovine aborted fetuses. Transbound Emerg Dis, 65, 158-165.
Garshasbi V., Naddaf S.R., Aghighi Z., Hassan N., Pooya M. & Mostafavi E. 2018. Leptospirosis in Caspian Sea littoral, Gilan Province, Iran. Acta Tropica, 181, 11-15.
Hassan N.A.D, Mohteshamuddin K., Al Aiyan A., Mohamed M.E.H., Biffa D.A. & Barigye R. 2018. Serological evidence of Brucella spp., Coxiella burnetii, Chlamydophilaabortus, and Toxoplasma gondii infections in sheep and goat herds in the United Arab Emirates. Proceedings, Neglected Tropical Diseases Congress: The Future challenges. December 05-06, 2018. Dubai, United Arab Emirates.
Kaveh A., Merat E., Samani S., Danandeh S. & Nezhad S. 2017. Infectious causes of bovine abortion in Qazvin Province, Iran. Archives of Razi Institute, 72, 225-230.
Kirkbride C.A. 1992. Etiologic agents detected in a 10-year study of bovine abortions and stillbirths. J Vet Diagn Invest, 4, 175-180.
Kirkland P.D. 2015. Akabane virus infection. Revue scientifique et technique, 34, 403-410.
Knudtson W.U. & Kirkbride C.A. 1992. Fungi associated with bovine abortion in the Northern Plains States (USA). J Vet Diagn Invest, 4, 181-185.
Lloyd C., Stidworthy M.F. & Ulrich W. 2010. Coxiella burnetii abortion in captive dama gazelle (Gazella dama) in the United Arab Emirates. J Zoo Wildl Med, 41, 83-89.
McCausland I.P., Slee K.J. & Hirst F.S. 1987. Mycotic abortion in cattle. Aust Vet J, 64, 129-132.
Michi A.N., Favetto P.H., Kastelic J. & Cobo E.R. 2016. A review of sexually transmitted bovine trichomoniasis and campylobacteriosis affecting cattle reproductive health. Theriogenol, 85, 781-791.
Muskens J., Wouda W., von Bannisseht-Wijsmuller T. & van Maanen C. 2012. Prevalence of Coxiella burnetii infections in aborted fetuses and stillborn calves. Vet Rec,170, 260.
Nusinovici S., Seegers H., Joly A., Beaudeau F. & Fourichon C. 2012. Increase in the occurrence of abortions associated with exposure to the bluetongue virus serotype 8 in naïve dairy herds. Theriogenol, 78, 1140-1151.
Okumu T.A, John N.M., Wabacha J.K., Tsuma V. & VanLeeuwen J. 2019. Seroprevalence of antibodies for bovine viral diarrhoea virus, Brucella abortus and Neospora caninum, and their roles in the incidence of abortion/foetal loss in dairy cattle herds in Nakuru District, Kenya. BMC Vet Res, 15, 95.
Pagmadulam B., Myagmarsuren P., Fereig R.M., Igarashi M., Yokoyama N., Battsetseg B. & Nishikawa Y. 2018. Seroprevalence of Toxoplasma gondii and Neospora caninum infections in cattle in Mongolia. Vet Parasitol Reg Stud Reports, 14, 11-17.
Rassouli M., Ahmadpanahi J. & Alvandi A. 2011. Prevalence of Sarcocystis spp. and Hammondia spp. microcysts in esophagus tissue of sheep and cattle, emphasized on their morphological differences. Parasitol Res, 113, 3801-3805.
Shabbir M.Z., Nazir M.M., Maqbool A., Lateef M., Shabbir M.A., Ahmad A., Rabbani M., Yaqub T., Sohail M.U. & Ijaz M. 2011. Seroprevalence of Neospora caninum and Brucella abortus in dairy cattle herds with high abortion rates. J Parasitol, 97, 740-742.
Thrusfield M., 2007. Veterinary epidemiology. 3rd ed. Hoboken, USA. Wiley-Blackwell, 230, 238-240.
Thurmond M.C. & Picanso J.P. 1990. A surveillance system for bovine abortion. Prev Vet Med, 8, 41-53.
Yağcı Yücel S., Yaman M., Kurt C., Babür C., Celebi B., Kılıç S. & Ozen D. 2014. Seroprevalance of brucellosis, listeriosis and toxoplasmosis in cattle in Adana Province of Turkey. Türkiye Parazitol Derg, 38, 91-96.
Yıldız K., Gökpınar S., Sürsal N. & Değirmenci R. 2017. Seroprevalence of Neospora caninum in dairy cattle raised in Çiçekdaği District of Kırşehir Province. Türkiye Parazitol Derg, 41, 135-138.