Seroprevalence of small ruminant lentivirus infections (SRLV) in family farming goats from Alagoas semiarid region, Brazil
DOI:
https://doi.org/10.12834/VetIt.3763.36046.2Keywords:
Goat, Epidemiology, Virus, AGIDAbstract
Small ruminant lentiviruses (SRLVs) are chronic and progressive diseases caused by retroviruses that pose a serious threat to family farming. This study aimed to determine the seroprevalence and risk factors associated with SRLV infection in goats from family farming properties in Alagoas, Northeastern Brazil. In the semiarid region of Alagoas, seventeen family farming properties were visited, distributed across eleven municipalities. An epidemiological questionnaire was administered to collect information on animal management practices and to identify potential risk factors for SRLV. Serological diagnosis of SRLV was performed using the agar gel immunodiffusion (AGID) technique with an in-house kit. Logistic regression analysis was conducted to identify factors associated with seropositivity for SRLV. A total of 388 goat serum samples were tested using AGID, resulting in a prevalence of 9.3% (36/388; 95% CI [0.0677–0.1258]). Logistic regression revealed one significant risk factor: “the type of farming” (p < 0.001; OR = 5.13; 95% CI [2.26–11.62]). Given the risk factor identified, it is essential to emphasize prophylactic measures against SRLV during prolonged stabilization periods. The detection of SRLV in family-run livestock operations in socially and economically vulnerable areas of Alagoas underscores the need for public policies that support family farming.References
Adams, D.S., Klevjer-Anderson, P., Carlson, J. L., McGuire, T. C., & Gorham, J. R. (1983). Transmission and control of caprine arthritis-encephalitis virus. American Journal of Veterinary Research. 44, 1670-1675.
Alves, R. V., Silva, A. S., Moura, J. B., Azevedo, C. A., Oliveira, N. G. C., Nascimento, S. A., Rodrigues, D. S., Almeida, B. F., Castro, R. S., & Higino, S. S. S. (2022.a). Epidemiological characterization of Lentiviruses in small ruminants in the immediate geographic region of Monteiro, Paraíba, Northeast, Brazil (in Portuguese). Research., Society and Development. 11 (14). Article e241111436258. http://dx.doi.org/10.33448/rsd-v11i14.36258.
Alves, R. V., Silva, A. S., Moura, J. B., Azevedo, C. A., Oliveira, N. G. C., Nascimento, S. A., Rodrigues, D. S., Almeida, B. F., Castro, R. S., & Higino, S. S. S. (2022b). Epidemiological survey of lentiviruses in small ruminants in western Cariri of Paraíba, Northeast Brazil (in Portuguese). Research., Society and Development. 11(14). Article e242111436264. http://dx.doi.org/10.33448/rsd-v11i14.36264.
Azevedo, D. A. A., Santos, V. W. S., Sousa, A. L. M., Peixoto, R. M., Pinheiro, R. R., Andrioli, A., & Teixeira, M. F. S. (2017). Small ruminant lentiviruses: economic and productive losses, consequences of the disease. Arquivos do Instituto Biológico. 84, 1-10. Article e0552016. https://doi.org/10.1590/1808-1657000552016.
Brasil. Casa Civil. (2006): Lei nº. 11.326, de 24 de julho de 2006. Estabelece as diretrizes para a formulação da Política Nacional da agricultura Familiar e Empreendimentos Familiares Rurais.
Buainain, A. M., Guanziroli, C. E., & Sabbato, A. D. (2004). Agricultura familiar: um estudo de focalização regional. In: Congresso da Sociedade Brasileira de Economia e Sociologia Rural, Cuiabá. Anais eletrônicos. Cuiabá: SOBER. Retrieved from http://www.sober.org.br/palestra/12/09O437.pdf.
Callado, A. K. C., Castro, R. S., & Teixeira, M. F. S. (2001). Lentiviruses of small ruminants (CAEV and Maedi-Visna): a review and perspectives. Pesquisa Veterinária Brasileira. 21, 87-97. https://doi.org/10.1590/S0100-736X2001000300001.
Carrozza, M. L., Niewiadomska, A. M., Said, M. M. M. R. A., Hué, S., Hughes, J., Gatseva, A., & Gifford, R. J. (2023). Emergence and pandemic spread of small ruminant lentiviruses. Virus Evolution. 9 (1), 1-12. https://doi.org/10.1093/ve/vead005.
Castro, R. S., Greeland, T., Leite, R. C., Gouveia, A. M. J., Mornex, J. F., & Cordier, G. (1999). Conserved sequence motifs involving the tat frame of Brazilian caprine lentiviruses indicate affiliations to both caprine arthritisencephalitis vírus and maedi-visna virus. Journal of General Virology. 80 (7),1583-1589.
Cecco, B. S., Henker, L. C., Lorenzett, M. P., Molossi, F. A., Schwertz, C. I., Baumbach, L. F., Weber, M. N., Canal, C. W., Driemeier, D., Pavarini, S. P., Langohr, I. M., Carossino, M., Balasuriya, U. B. R., & Sonne, L. (2022). An outbreak of visna-maedi in a flock of sheep in Southern Brazil. Braz J Microbiol. 53 (3),1723-1730. doi: 10.1007/s42770-022-00763-9. Epub 2022 Apr 27.
Costa, L. S. P., Lima, P. P., Callado, A. K. C., Nascimento, S. A. & Castro, R. S. (2007). Small Ruminant Lentivirus in Santa Inês Ovines: isolation, identification by PCR and serological survey in the State of Pernambuco, Brazil. Arquivos do Instituto Biológico, São Paulo. 74 (1), 11-16. jan./mar. https://doi.org/10.1590/1808-1657v74p0112007.
Dawson, M. (1980): Maedi/Visna: a review. Veterinary Record. 106, 212-216. https://doi.org/ 10.1136/vr.106.10.212.
Herbelê, A. L. O. (2017). Agricultura familiar e pesquisa agropecuária: contribuições para uma agenda de futuro. In: Delgado, G. C., Bergamasco, S. M. P. P. (orgs.). Agricultura familiar brasileira: desafios e perspectivas de futuro. Brasília: Ministério do Desenvolvimento Agrário. p. 131-148.
Hosmer, D. W. & Lemeshow, S. (2013). Applied Logistic Regression (3ª ed.). Wiley.
Kalogianni, A. I., Stavropoulos, I., Chaintoutis, S. C., Bossis, I., & Gelasakis, A. I. (2021). Serological, Molecular and Culture-Based Diagnosis of Lentiviral Infections in Small Ruminants. Viruses.13(9),1711. doi: 10.3390/v13091711.
Luz-Armendáriz, J., Watty, A. E. D., Mendoza, H. R., Núñez, L. G., Loza, C. T., Domínguez, E. M. C., Aparicio, E. D., & Benítez, J. F. R. (2021). Prevalence, molecular detection, and pathological characterization of small ruminant lentiviruses in goats from Mexico. Small Ruminant Research. 202 106474. https://doi.org/10.1016/j.smallrumres.2021.106474.
Megid, J., Ribeiro, M. G., & Paes, A. C. (2016). Doenças Infecciosas em animais de produção e companhia, 1ª ed., Roca, Rio de Janeiro.
Oliveira, M. M. M., Melo, M. A., Andrade, P. P., Gomes, S. M., Campos, A. C., Nascimento, S. A., & Castro, R. S. (2008). Western blot for the diagnosis of small ruminant lentivirus infections in goats: a simple method for antigen production. Arquivos do Instituto Biológico, São Paulo. 75 (3), 263-270. jul./set. https://doi.org/10.1590/1808-1657v75p2632008.
Peretz, G., Asso, J., & Devillechaise, P. (1993). Le C.A.E.V.: revue des connaissances actuelles et consequences pratiques. Revué de Médecine Vétérinaire. 144 (2), 93-98.
Pinheiro, R. R., & Gouveia, A. M. G. (2001). Prevalence of caprine arthritis encephalitis virus infection in the State of Ceará, Brazil (In Portuguese). Ciência Rural. 31, 449-454. https://doi.org/10.1590/S0103-84782001000300014.
Rizzo, H., Jesus, T. K. S., Castro, R. S., Pinheiro Júnior, J. W., Soares, L. L. S., Oliveira, C. C. M., Nascimento, S. A., & Silva, T. R. (2018). Occurrence and risk factors associated with small ruminant lentivirus infection in the State of Sergipe, Brazil. Pesquisa Veterinária Brasileira. 38 (6),1043-1050. junho 2018. https://doi.org/10.1590/1678-5150-PVB-5363.
Rocha, J. A. S., Silva, K. J. P. O., Almeida, B. F., Vieira, A. M., Nascimento, S. A., Maia, R. C. C., & Pinheiro Júnior, J. W. (2022). Lentiviroses de pequenos ruminantes: perguntas e respostas. 1ª ed., EDUFRPE, Recife.
Rodrigues, L. F. S., Oliveira, M. E. F., Teixeira, P. P. M., Cavalcante, I. J. M., & Vale, M. R. (2012). Adenosine deaminase activity as a biochemical marker of inflammatory response in goats infected by caprine arthritis encephalitis virus. Small Ruminant Research. 108 (1-3), 20-126.
Shah, C., Boni, J., Huder, J. B., Vogt, H. R., Muhlherr, J., Zanoni, R., Miserez, R., Lutz, H., & Schupbach, J. (2004). Phylogenetic analysis and reclassification of caprine and ovine lentiviruses based on 104 new isolates: evidence for regular sheep-to-goat transmission and worldwide propagation through livestock trade. Virology. 319 (1), 12-26. https://doi.org/10.1016/j.virol.2003.09.047.
Sousa, M. M., Andrioli, A., Pinheiro, R. R., Alves, F. S. F., Santos, V. W. S., Damasceno, E. M., Sousa, A. L. M., & Vieira, L. S. (2019). An epidemiological study of caprine arthritis encephalitis virus (CAEV) in breeder goats from Northeastern Brazil. Semina: Ciências Agrárias. 40 (5), 1857-1866. https://doi.org/ 10.5433/1679-0359.2019v40n5p1857.
Souza, T.S., Pinheiro, R.R., Lima, C.C.V., & Costa, J.N. (2012). Interspecies transmission of small ruminant lentiviruses: review and challenges. Acta Veterinaria Brasilica. 6 (1), 23-34.
Souza, K. C., Pinheiro, R. R., Santos, D. O., Brito, R. L. L., Rodrigues, A. S., Sider, L. H., Paula, N. R. O., Avila, A. A., Cardoso, J. F. S., & Andrioli, A. (2013). Transmission of the caprine arthritis-encephalitis vírus through artificial insemination. Small Ruminant Research.109, 193-198. https://doi.org/10.1016/j.smallrumres.2012.07.031.
Souza, E. O., Costa, M. S., Oliveira Júnior, J. F., Gois, G., Mariano, G. L., Costa, C. E. S., Correia Filho, W. L. F., & Santiago, D. B. (2020). Erosivity Estimation and Spatialization in Climatic Mesoregions in the State of Alagoas. Revista Brasileira de Meteorologia. 35, 769-783. https://doi.org/10.1590/0102-77863550005.
Teixeira, W. C., Santos, H. P., Veschi, J. L. A., Nascimento, S. A., Silva, J. C. R., Marvulo, M. F. V., Rizzo, H., & Castro, R. S. (2016). Prevalence of caprine arthritis virus infection in goat herds in the state of Maranhão, Brazil. Revista Brasileira de Medicina Veterinária. 38 (1),1-6. jan/mar.
Teles, J. A. A., Nascimento, S. A., Melo, E. X., Almeida, E. C., Marvulo, M. F. V., Rizzo, H., Nogueira, D. B., Azevedo, S. S., Silva, J. C. R., & Castro, R. S. (2023). Factors associated with small ruminant lentivírus infection in goat herds from Pernambuco state, Northeast region of Brazil. Preventive Veterinary Medicine. 211: 105814. https://doi.org/10.1016/j.prevetmed.2022.105814.
Thrusfield, M. (2007). Veterinary epidemiology. 3ª ed., Blackwell Science Ltd., Oxford.
Vilela, S.L.O. (2017). Perspectivas para a agricultura familiar brasileira: elementos de um projeto político de desenvolvimento rural, para além de uma “questão tecnológica”. In: Delgado, G. C., Bergamasco, S. M. P. P (orgs.). Agricultura familiar brasileira: desafios e perspectivas de futuro. Brasília: Ministério do Desenvolvimento Agrário, 2017. p. 244-262.
Zar, J.H. (1999). Biostatistical Analysis. 4ª ed., Prentice Hall, Upper Saddle River, New Jersey.
